If an ancient amphibian lost a limb or a tail, it could simply sprout a new one, according to researchers who found fossil evidence of limb regeneration dating back 290 million years.
The finding shows that some Carboniferous and Permian period animals had regenerative abilities a full 80 million years before salamanders, one of the few modern-day animal groups that can fully regenerate their limbs and tail, existed in the fossil record.
The fact that other tetrapods — a group comprised of four-legged vertebrates, including amphibians, reptiles, mammals and birds — had regenerative abilities suggests there are multiple ways to regrow limbs, said study lead researcher Nadia Fröbisch, a paleontologist at the Natural History Museum in Berlin. [Slithery, Slimy: Images of Legless Amphibians]
“Regenerative medicine is an active and very large research field,” Fröbisch told Live Science. Most regenerative medicine is focused on the molecular mechanisms used by modern salamanders, but “we don’t only have to look for things specific to salamanders, but also mechanisms present in all tetrapods,” she said.
Fröbisch has studied limb regeneration in salamanders for years. She’s not alone — at least 100 years ago, researchers noted that salamander limbs develop differently than those of all other tetrapods, and wondered